4 days ago · The leading international peer-reviewed journal for perinatal & neonatal medicine research and reviews. An official journal of the RCPCH.

Archives of Disease in Childhood is an international peer review journal that aims to keep paediatricians and others up to date with advances in the diagnosis and treatment of childhood diseases as well as advocacy issues such as child protection. It focuses on all aspects of child health and disease from the perinatal period (in the Fetal and Neonatal edition) through to …

Objective Caffeine is widely used in preterm infants to prevent or treat apnoea of prematurity. Adverse gastrointestinal effects of caffeine have not been thoroughly researched in preterm infants. With this systematic review and meta-analysis, we aim to summarise the results of trials on the gastrointestinal effects of caffeine in preterm infants. …

The fetus depends on the mother for placental exchange of oxygen and carbon dioxide. This in turn relies on adequate maternal blood gas concentrations, uterine blood supply, placental transfer and fetal gas transport. Disruption of any of these can cause fetal hypoxia, which, despite compensatory mechanisms, may lead to acidosis. When severe and …

Feb 17, 2023 · Pramod Puligandla, Erik Skarsgard, Robert Baird, Elena Guadagno, Alexandra Dimmer, Olivia Ganescu, Nimrah Abbasi, Gabriel Altit, Mary Brindle, Sairvan Fernandes, Shyamala Dakshinamurti, Helene Flageole, Audrey Hebert, Richard Keijzer, Martin Offringa See the full list of authors

Postnatal cytomegalovirus (pCMV) infection is a common viral infection typically occurring within the first months of life. pCMV refers to postnatal acquisition of CMV rather than postnatal manifestations of antenatal or perinatal acquired CMV. pCMV is usually asymptomatic in term infants, but can cause symptomatic disease in preterm (gestational age <32 weeks) and very low birth weight (<1500 ...

Objective To measure within-subject changes in ventilation/perfusion (V′/Q′) mismatch in response to a protocol of individualised nasal continuous positive airway pressure (CPAP) level selection. Design Single-arm, non-randomised, feasibility trial. Setting Three centres in the Children’s Hospital of Philadelphia neonatal care network. Patients Twelve preterm infants of postmenstrual age ...

Objective Therapeutic hypothermia (TH) for neonatal hypoxic-ischaemic encephalopathy (HIE), delivered mainly in tertiary cooling centres (CCs), reduces mortality and neurodisability. It is unknown if birth in a non-cooling centre (non-CC), without active TH, impacts short-term outcomes. Design Retrospective cohort study using National Neonatal Research Database and propensity score-matching ...

INTRODUCTION The management and diagnosis of early onset sepsis (EOS) in term and preterm infants continues to evolve with wide variation in practice glob-ally. With the declining incidence of EOS, and a growing emphasis on reducing neonatal exposure to prolonged and unnecessary antimicrobials, many national organisations have updated their diag-nostic and treatment guidelines. Given the broad ...

Archives of Disease in Childhood: Fetal & Neonatal adheres to the highest standards concerning its editorial policies on publication ethics, scientific misconduct, consent and peer review criteria. The journal follows guidance produced by bodies that include the Committee on Publication Ethics (COPE), the World Association of Medical Editors (WAME) and the …