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  1. Bispectral index (BIS) monitoring of ICU patients on continuous ...

    Mar 21, 2000 · Patients with severe brain injury (GCS ≤ 8) were excluded. In months one and two, sedatives were titrated to patient comfort guided by vital sign changes after stimulation. …

  2. Evaluating and monitoring analgesia and sedation in the intensive …

    May 14, 2008 · The BIS (Aspect Medical Systems, Norwood, MA, USA) is composed of time domain, frequency domain, and high-order spectral subparameters. This integrates several …

  3. Strategies to optimize analgesia and sedation - Critical Care

    May 14, 2008 · Achieving adequate but not excessive sedation in critically ill, mechanically ventilated patients is a complex process. Analgesics and sedatives employed in this context …

  4. Airway pressure release ventilation increases cardiac performance …

    Jul 2, 2001 · Background The purpose of the present study is to determine whether airway pressure release ventilation (APRV) can safely enhance hemodynamics in patients with acute …

  5. A narrative review on the future of ARDS: evolving definitions ...

    Feb 24, 2025 · Acute respiratory distress syndrome (ARDS) is a severe complication of critical illness, characterized by bilateral lung infiltrates and hypoxemia. Its clinical and …

  6. Peri-intubation adverse events and clinical outcomes in emergency ...

    Apr 17, 2025 · Background Emergency tracheal intubation in critically ill patients carries a high risk of complications, and practices vary substantially across different settings. Identifying risk …

  7. Pain and sedation management and monitoring in pediatric …

    Mar 31, 2022 · Background Management and monitoring of pain and sedation to reduce discomfort as well as side effects, such as over- and under-sedation, withdrawal syndrome …

  8. Management of severe acute respiratory distress syndrome: a …

    Jul 18, 2023 · This narrative review explores the physiology and evidence-based management of patients with severe acute respiratory distress syndrome (ARDS) and refractory hypoxemia, …

  9. The efficacy and safety of prokinetic agents in critically ill patients ...

    Aug 15, 2016 · Background Intolerance to enteral nutrition is common in critically ill adults, and may result in significant morbidity including ileus, abdominal distension, vomiting and potential …

  10. Opioid-induced constipation in intensive care patients: relief in …

    Jul 1, 2008 · Constipation is the most common gastrointestinal complication associated with opioid therapy in chronic pain patients, and also frequently occurs in sedated intensive care …