Infection of mucosal cells results in cellular destruction and desquamation of the superficial mucosa. The resulting edema and mononuclear cell infiltration of the involved areas are accompanied by such symptoms as nonproductive cough, sore throat, and nasal discharge.

Infections occur through contact with these bodily fluids or with contaminated surfaces. Out of a host, flu viruses can remain infectious for about one week at human body temperature, over 30 days at 0 °C (32 °F), and indefinitely at very low temperatures (such as lakes in …

Jun 2, 2024 · Orthomyxoviridae is a family of enveloped RNA viruses known for their ability to cause significant respiratory illnesses in humans and animals. These viruses are responsible for seasonal influenza outbreaks and have also been associated with occasional pandemics throughout history.

Orthomyxoviridae contains four genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, and Thogotovirus. The influenza viruses are known for periodically giving rise to pandemic outbreaks in humans.

Thogoto virus, the type species for the genus, can infect humans and causes disease in livestock and other mammals. Another species, Dhori virus, is also capable of infecting humans. Nonetheless, they are not generally important human pathogens because of …

May 29, 2008 · Research work is centered on biotechnology to produce immunogenic peptides and proteins and more logical searches for antivirals using amino acid sequence data and also virus specific enzymes such as the virion transcriptase as targets.

The Orthomyxoviridae (influenza viruses) are a major determinant of morbidity and mortality caused by respiratory disease, and outbreaks of infection sometimes occur in worldwide epidemics. Influenza has been responsible for millions of deaths worldwide.

The orthomyxoviridae family containing influenza A, B and C viruses are enveloped RNA viruses, which cause upper respiratory tract infections characterized by fever, chills, headache, generalized muscular aching, and loss of appetite …

Animal reservoirs may harbor viruses which, through genetic reassortant, become infectious for humans. Clinical Manifestations: Rapid onset of malaise, fever, and myalgia, usually with nonproductive cough or sore throat. May often be subclinical.

Nov 15, 2019 · The viruses under the family Orthomyxoviridae are responsible for a variety of important respiratory diseases in humans and different animal species. The seven genera under the family are the influenza viruses A, B, C and D, Quaranjavirus, Thogotovirus and Isavirus.