For decades, the biology of the intestinal stem cells was considered analogous to that of well-studied hematopoietic stem ...

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The necrosome is the key macromolecular signaling platform initiating necroptosis, i.e., a RIPK1/RIPK3-dependent program of cell death with an important role in the control of inflammation in ...

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During PINK1- and Parkin-mediated mitophagy, autophagy adaptors are recruited to damaged mitochondria to promote their selective degradation. Autophagy adaptors such as optineurin (OPTN) and NDP52 ...

Several bacterial species have been implicated in the development of colorectal carcinoma (CRC), but CRC ‐associated changes of fecal microbiota and their potential for cancer screening remain to be ...