The Detroit Lions visit the San Francisco 49ers in an NFC title game rematch that features both teams going different ...

The Lions might be down another starting quarterback entering their Week 17 contest against the San Francisco 49ers on Monday ...

The 49ers (6-9) placed left tackle Trent Williams on injured reserve Thrusday, the result of an ankle injury that will have ...

Detroit tallied a blowout road victory over the Chicago Bears in Week 17, while the San Francisco 49ers fell to the Miami ...

Offensive tackle Jaylon Moore was officially placed on IR with a quad injury he sustained in the 49ers’ Week 16 loss to the ...

On the day the San Francisco 49ers were eliminated from playoff contention, they delivered a performance that summed up their ...

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

ESPN's Football Power Index rates the 49ers' playoff chances at less than 1% entering Week 16, making it extremely unlikely ...

The 49ers have had a season filled with disappointment and one NFL writer believes they will look to the NFC to replace one ...

Tua Tagovailoa threw the 100th passing touchdown of his career, and the Miami Dolphins defeated the San Francisco 49ers on ...

Tua Tagovailoa threw for 215 yards and a touchdown, Jason Sanders nailed five field goals, and the Miami Dolphins kept their ...

San Francisco 49ers at Miami Dolphins Preview: The 6-8 San Francisco 49ers travel to Miami to take on the 6-8 Dolphins. After ...