Paraneoplastic syndrome represents a major systemic complication in cancer patients but its causes remain unclear. This study ...

Paraneoplastic syndromes affect multiple organs and are a central cause of mortality in cancer patients. In this issue, Cong et al ( 2025) report an inflammatory gut-kidney axis mediating systemic ...

Understanding the interplay between immune cells and targeted cancer therapies is crucial for advancing oncological treatments. While targeted therapies ...

To effectively battle cancer, scientists must study the battlefield. Now, in a recent study published in Nature ...

To effectively battle cancer, scientists must study the battlefield. Now, in a recent study published in Nature ...

Tumor microenvironment (TME) plays a pivotal role in malignant progression and metastatization in several tumors, including ...

Hyundai ADM Bio (KOSDAQ symbol 187660) today announced the voluntary withdrawal of its Investigational New Drug (IND) ...

However, Hyundai Bioscience's latest findings show that the actual obstacle lies in stiffened ECM that prevents immune cells and antibodies from reaching the tumor core. Penetrium™ remodels the ECM, ...

1Cancer Biomaterials Engineering Laboratory, Cancer Innovation Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland.

Although advances in genomic technologies have resulted in remarkable progress in understanding the pathogenesis of DLBCLs, the characterization of the tumor microenvironment (TME) and spatial ...

Six months of treatment with dostarlimab led to nonoperative management in 80% of patients with stages I-III MMRd rectal and non-rectal tumors. And in all patients who had a clinical complete ...

Adoptive cell therapy based on ex-vivo expanded tumor-infiltrating lymphocytes (TILs) has historically been most effective in the treatment of metastatic melanoma, 1 with objective response rates of ...