More information: Abstract no: 12, "On-target mutations drive resistance to WRN helicase inhibitors in microsatellite ...

Although pembrolizumab is approved for deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) tumors regardless of histology, there is a paucity of data to support its effectiveness ...

Microsatellite instability (MSI) is a “striking” prognostic factor for patients with gastric cancer, even after controlling for clinicopathologic characteristics, according to researchers. The ...

What Is a Brain Tumor? A brain tumor (also called an intracranial tumor) is a cluster of abnormal cells that grows in or around your brain. There are over a hundred types of tumors that develop in ...

The ability to detect serrated polyps by fecal blood testing, computed tomographic (CT) colonography and colonoscopy is limited. Serrated polyps are less likely than adenomas to bleed, so fecal ...

Nov. 12, 2024 — Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells ...

The FDA recently approved a phase 2 clinical trial to investigate the efficacy of leronlimab in patients with relapsed or ...

Oct. 30, 2024 — A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor ...

Thyroid cancer is a type of cancer that starts in your thyroid gland. A gland is an organ in your body that makes a substance. Your thyroid is shaped like a small butterfly and is found inside the ...

Hormone therapy (also called hormonal therapy or endocrine therapy) slows or stops the growth of hormone-sensitive tumors by blocking ... it causes the receptor to be unstable and vulnerable ...

(ends) Abstract no: 12, “On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer”, by Gabriele Picco, presented in plenary session 7 ...