More information: Abstract no: 12, "On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer", by Gabriele Picco, presented in plenary session 7 ...

(ends) Abstract no: 12, “On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer”, by Gabriele Picco, presented in plenary session 7 ...

More information: Abstract no: 12, "On-target mutations drive resistance to WRN helicase inhibitors in microsatellite ...

Professor Yoon Jong-hyuk (Gastrointestinal Surgery) of Cheonan Hospital, affiliated with Soonchunhyang University, recently won the Excellence Researcher Awar ...

“Ultimately, if the tumor is microsatellite unstable, that always makes us question whether somebody was born with a genetic syndrome. They may or may not have been, but they should be tested. The ...

Most colorectal cancer (CRC) cases are secondary to an existing adenoma ... and were more likely to be poorly differentiated, microsatellite unstable, and KRAS-wild. Overall, adenocarcinoma arising ...

The FDA recently approved a phase 2 clinical trial to investigate the efficacy of leronlimab in patients with relapsed or ...

Although pembrolizumab is approved for deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) tumors regardless of histology, there is a paucity of data to support its effectiveness ...

Microsatellite instability (MSI) is a “striking” prognostic factor for patients with gastric cancer, even after controlling for clinicopathologic characteristics, according to researchers. The ...

The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to ... Researchers Home in on Tumor Vulnerabilities to Improve Odds of ...

Doctors were convinced that a Norwegian man was simply fat for 12 years — but his growing belly was actually expanding with a 60-pound malignant tumor. He was diagnosed with obesity and even got ...