They discovered a novel line of communication between metastatic medulloblastoma and leptomeningeal fibroblasts that mediates recruitment and reprogramming of the latter to support tumor growth.

They discovered a novel line of communication between metastatic medulloblastoma and leptomeningeal fibroblasts that mediates recruitment and reprogramming of the latter to support tumor growth.

Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. Nature Cell Biology , 2025; DOI: 10.1038/s41556-025-01660-7 ...

Among these, Medulloblastoma stands out due to its aggressive nature and prevalence in younger populations. It is a rare and aggressive type of brain tumour that primarily affects children but can ...

SickKids researchers identified the KCNB2 gene as a key driver of medulloblastoma tumor growth. Blocking KCNB2 disrupts potassium channels, causing tumor-propagating cells to swell and lose integrity.

A study published in Nature Genetics reveals new insights into how medulloblastoma, the most common malignant brain tumor of childhood, can arise as the cerebellum develops. Researchers discovered ...

Medulloblastoma is the most common malignant brain tumor (in the cerebellum) in children, with survival rates varying across its four subtypes. Historically, Group 3 medulloblastoma has the ...

A drug that was developed to treat pancreatic cancer has now been shown to increase symptom-free survival in preclinical medulloblastoma models -- all without showing signs of toxicity. A drug ...

Medulloblastoma (the most common malignant childhood brain tumor) is separated into four molecular groups, with Group 3 bearing the worst prognosis. By studying EP300 and CBP, critical proteins in ...

Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years of experience in consumer-facing health and wellness content. Michael Strahan’s daughter Isabella revealed ...

On Thursday, Strahan and his 19-year-old daughter, Isabella, opened up about the diagnosis of the rare brain cancer called medulloblastoma on Good Morning America. Isabella was diagnosed in ...

In an interview with anchor Robin Roberts, the father-daughter duo shared that Isabella was diagnosed with medulloblastoma in the fall. “I didn’t notice anything was off until probably ...