Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells ...

Researchers from The University of Texas MD Anderson Cancer Center have identified a new biomarker, TTF-1, that was ...

Amidst the continued struggle to treat non-small-cell lung cancer, a new study led by Stanford University scientists suggests that a patient's response to immunotherapy may hinge on how immune cells ...

Tumor microenvironment (TME) plays a pivotal role in malignant progression and metastatization in several tumors, including ...

TLN1 upregulation is associated with poor disease- free survival (DFS) in triple- negative breast cancer (TNBC). (B) Representative immunohistochemistry images of TLN1 expression in TNBC tissue, chest ...

1Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, Florida. 2Immunology, Genome Regulation and Cell Signaling Program, The Wistar Institute, Philadelphia, Pennsylvania. 3Department of ...

Small integrin-binding ligand N-linked ... in the near proximity of cancer cells, a dynamically changing microenvironment that supports the key local steps that need to be temporally and spatially ...

Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo and Biosensing, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, Hunan ...

In cancer, EVs often depart from tumor cells to ... The researchers focused on understanding the role of integrin heterodimers, which are molecules that help sEVs adhere to the host cell.

In this study, we review the mechanisms by which immunotherapy influences skeletal muscle, focusing on immune-related myositis, inflammation, and metabolic alterations within the tumor ...

Although advances in genomic technologies have resulted in remarkable progress in understanding the pathogenesis of DLBCLs, the characterization of the tumor microenvironment (TME) and spatial ...