Epigenetics research in Japan is poised for significant growth, driven by advances in biotechnology and a growing emphasis on personalized medicine. As the rest of the world leans towards more ...

Post-translational changes to the histone proteins that help package DNA into chromosomes. These changes include methylation and acetylation, which influence chromatin structure and gene ...

To investigate genetic and epigenetic issues stimulating the evolution of primary trastuzumab resistant and sensitive breast cancer, we compared genomic variation, histone modification and DNA ...

MENLO PARK, Calif., April 22, 2025 /PRNewswire/ -- GRAIL, Inc. (Nasdaq: GRAL), a healthcare company whose mission is to detect cancer early when it can be cured, will present new data highlighting ...

Uncovering methylation signatures and pathways associated with resistance to anti-EGFR therapy in colorectal cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual ...

Tanas. The ATAC histone acetyltransferase complex is a key oncogenic driver in sarcomas [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2025; Part 1 (Regular ...

These interventions can induce epigenetic modifications (including histone acetylation, DNA methylation, long non-coding RNA, and miRNA regulation) that affect key metabolic pathways such as ...

Their rampant use has led to an increase in the prevalence of various chemical toxicity-induced diseases, including hormonal disruption, cancer ... frequency and histone acetylation levels.

School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China ...