The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

This review highlights the critical role of epigenetic regulation in nuclear receptor function, shedding new light on its ...

New data show early hints of the medicine improving patient survival — the gold standard outcome of any cancer study. The drug, ivonescimab, was approved for previously untreated patients with ...

Post-translational changes to the histone proteins that help package DNA into chromosomes. These changes include methylation and acetylation, which influence chromatin structure and gene ...

MENLO PARK, Calif., April 22, 2025 /PRNewswire/ -- GRAIL, Inc. (Nasdaq: GRAL), a healthcare company whose mission is to detect cancer early when it can be cured, will present new data highlighting ...

While cancer immunotherapies have revolutionized treatment, their efficacy remains limited for most patients, highlighting tumors' capacity to evade immune detection. Epigenetic modifications, ...

Combining DNA methylation inhibition and STING agonist in the treatment of metastatic triple-negative breast cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual ...

Children accounted for 4.2% of the scans. The researchers excluded tests in the patient’s last year of life because it was unlikely to lead to cancer. Adults 50 to 59 had the highest number of ...

These interventions can induce epigenetic modifications (including histone acetylation, DNA methylation, long non-coding RNA, and miRNA regulation) that affect key metabolic pathways such as ...