Medscape9d
Neutrophil Dysfunction in Older Adults With Pneumonia: Not a Glycolysis Problem After All
Neutrophil function was impaired, but glycolysis was unaffected in hospitalized older adults with community-acquired ...
ING5 inhibits aerobic glycolysis of lung cancer cells: Study
Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis ...
GEN13d
Mitochondrial Toxicity Early Alert System
Biocell Energetics measures extracellular flux in real time which helps drug developers identify drug-induced mitochondrial ...
BMJ14d
Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages
Objective Macrophage activation by monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals mediates an interleukin (IL)-1β-dependent inflammation during gout and pseudo-gout flare, ...
eLife20d
TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1α axis in melanoma
This important study investigates the molecular mechanisms underpinning how the tumor necrosis factor alpha-induced protein (TIPE) regulates aerobic glycolysis to promote tumor growth in melanoma.
C&EN23d
Ultrasensitive Protein Aggregate Quantification Assays for Neurodegenerative Diseases on the Simoa Platform
Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, U.K. UK Dementia Research Institute at University of Cambridge, Cambridge CB2 0XY, U.K. Yusuf Hamied Department of ...
C&EN1mon
Permeability-Engineered Compartmentation System-Enabled Digital PCR (PECS-dPCR): A Digital Platform toward Multistep Biomolecular Assays
State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China School of Physical Science and ...
Frontiers1y
BNT162b2 COVID-19 vaccination in children alters cytokine responses to heterologous pathogens and Toll-like receptor agonists
Background: Vaccines can have beneficial off-target (heterologous) effects that alter immune responses to, and protect against, unrelated infections. The heterologous effects of COVID-19 vaccines have ...