Semiconservative replication was not the only model ... DNA unwinding at a single spot on the chromosome known as the replication origin. As the double helix unwinds, it creates a loop known ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.

However, SMC machines don't naturally know which parts to connect. They simply load somewhere on the DNA and start shaping it into a loop until they reach a point where they are forced to stop. That's ...

The second possibility is the semi-conservative model, which suggests that H3–H4 dimers or tetramers are distributed equally between both strands following DNA replication (Fig. 3B). The ...