New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

Our blood consists of many cell types that develop through different stages from a precursor type—the blood stem cell. An ...

Last November, results from the MITIGATE trial made headlines at ACR Convergence 2024 with positive phase 3 trial data for inebilizumab, an IgG1 monoclonal antibody targeting CD19, in patients with ...

Northwestern Medicine investigators have uncovered new insights into how intercellular "glue" functions to enable ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating ...

GC Cell (KRX:144510), under the leadership of CEO Sungyong Won, announced today the initiation of its domestic Phase 1 clinical trial for GCC2005 (AB‑205), a novel CD5 CAR‑NK cell therapy. This "first ...

Gated on live, CD5+ cells that were stained for CAR using a biotinylated ... prevent or treat CRS in a clinically relevant model with spontaneous and aggressive B cell malignancies. Recent evidence ...

A transitional B cell population with a distinct transcriptomic signature was expanded in TN-JDM and characterized by higher CD24 and CD5 proteins and less CD39, an immunoregulatory protein. This data ...

Flow cytometry is used to analyze the cell surface markers CD45, CD3, CD5, CD19, CD10, CD20, and kappa/lambda. 2,9 Cytogenetics or FISH assesses for chromosomal translocations to identify t(14;18), ...