Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes ...

Rocket Pharmaceuticals has shared early data from three patients that tie its gene therapy for an inherited heart disease to ...

In a new study published in Cell Reports, researchers at the University of Freiburg reveal how a disordered protein segment helps connect two key steps of gene expression: the reading of genes and the ...

Joint study by University of Shizuoka, Kobe University, and Noster Inc. uncovers a novel postbiotic pathway for obesity ...

Department of Endocrinology and Metabolism, Affiliated Hospital of Qingdao University, Qingdao 266003, P. R. China Qingdao Key Laboratory of Thyroid, Diseases, Medical Research Center, Qingdao 266555, ...

Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P. R. China Shanghai TCM-Integrated Institute of Vascular Anomalies, Shanghai ...

RNA sequencing and western blot revealed that WED-induced megakaryocyte differentiation involves the regulation of mitochondrial oxidative phosphorylation mediated by the AMPK signaling pathway and ...

Our findings demonstrate that DAPA can inhibit the MAPK signaling pathway, as confirmed by network ... whether DAPA’s inhibition of MAPK synergizes with other aging-related pathways (e.g., AMPK or ...

Department of Biochemistry and Biophysics, College of Agriculture and Life Sciences, Texas A&M University, College Station, Texas 77843, United States ...

Decoupling AKAP11-PKA from autophagy alters downstream phosphorylation events, supporting an autophagy-dependent checkpoint for PKA signaling. Ablating AKAP11 in induced pluripotent stem cell-derived ...