In this valuable study, Roiuk et al employed a combination of ribosome profiling and reporter assays to provide convincing evidence that eIF2A is not involved in translational regulation in cultured ...

"We are thrilled to welcome Nerissa to the Alltrna leadership team as we advance our first tRNA development candidates to the clinic for liver Stop Codon Disease," said Michelle C. Werner ...

Alltrna, a Flagship Pioneering company unlocking transfer RNA (tRNA) biology and pioneering tRNA therapeutics to regulate the protein universe and resolve disease, today announced the appointment of ...

tRNA Q34 modification impacts tyrosine codon decoding and leads to proteome reprogramming in response to antibiotic stress in Vibrio cholerae.

As humans, we often focus on viruses and bacteria because of their role in causing various, sometimes severe, diseases.

Long tDNA clusters with more than 10 repeated tRNA gene units were visualized using the ChromoMap R package (Anand and Rodriguez Lopez, 2022). On average, less than half of all tRNA genes of each ...

Protein synthesis is made up of two stages, transcription and translation. The processes our cells undergo to turn the instructions found in genes in our DNA into the proteins they code for is broadly ...

A pipeline to select optimal markers for microbial phylogenomics and species tree estimation using the multispecies coalescent and concatenation approaches ...