Deebo Samuel revealed why San Francisco quarterback Brock Purdy was upset after Sunday's win over the Tampa Bay Buccaneers.

Here are your top 49ers storylines for Wednesday, November 13th.

San Francisco treaded water without Christian McCaffrey. Now that the NFL's reigning Offensive Player of the Year is back, it ...

The San Francisco 49ers earned a hard-fought victory on Sunday against the Tampa Bay Buccaneers, securing back-to-back wins ...

San Francisco 49ers quarterback Brock Purdy was announced as NFL Slimetime's "Nickelodeon Valuable Player" for Week 10.

Asked how it must have felt for Moody to go from the 49ers' biggest loser to the hero of the show, Kyle Shanahan broke down ...

San Francisco 49ers tight end George Kittle has two objectives for this season — remain healthy and win a Super Bowl.

Former Super Bowl-winning coach Jon Gruden is looking to jump back into the NFL coaching fray, according to Boomer Esiason.

Kittle injured his hamstring during the 49ers’ Week 10 win over the Tampa Bay Buccaneers. Shanahan told reporters in a press ...

The San Francisco 49ers are preparing for their Week 11 contest against the Seattle Seahawks on Sunday at Levi's Stadium in ...

Tom Brady always had to compete for the job of the starting whether it was NFL, college or at high school even when team wasn ...

Tampa Bay Buccaneers quarterback Baker Mayfield has been playing some of the best football in the NFL — and he could join Tom ...