A primary function of the TNF superfamily molecules is to regulate cell survival. In addition, signals from OX40, 4-1BB, CD27 and DR3 also synergize with T-cell receptor (TCR) signals to allow ...

We’re witnessing a renaissance in cytokine targeting,” says Dr. Emily Rhodes, immunologist at the Stanford Institute for ...

How CD4+ T cells respond to Chikungunya virus may trigger long-lasting joint pain, mimicking autoimmune disease long after ...

CHIKV can trigger long-term joint pain that mimics autoimmune diseases like rheumatoid arthritis, potentially due to ...

The process of necrosis, a form of cell death, may represent one of the most promising ways to change the course of human ...

By studying Chikungunya virus, scientists shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune disease.

However, you can take these drugs if you have basal cell carcinoma ... certolizumab, a TNF inhibitor you take by injection. Studies have shown that this medication doesn’t cross the placenta.