The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San ...

Detroit Lions coach Dan Campbell remains haunted by January's NFC Championship Game in San Francisco. For Campbell, it still ...

Not surprisingly, as he prepares to take his team back to San Francisco, Lions coach Dan Campbell is still haunted by the ...

Who are the 10 greatest San Francisco 49ers of all time? FOX Sports Research compiled the list of Niner greats.

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

As the 49ers look to play spoiler against the Lions on Monday Night Football, RB Isaac Guerendo got a positive injury update.

The Miami Dolphins inched closer to finishing their season with a winning record by beating the San Francisco 49ers a week ...

The Detroit Lions are set to play their second-to-last game of the season on the road against the San Francisco 49ers, but ...

The Rams (10-6) have won five straight games despite scoring a combined 44 points over their last three contests, also ...

The Dolphins are running out of time and games. They're holding on to hope. Miami's chances of making the AFC playoffs are ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...