Purpose: Data collected from the Food and Drug Administration (FDA) under the Freedom of Information Act are presented to help clinicians understand the data prompting the black-box warning for ...

Trained nurses in most critical care settings often administer propofol safely to patients who are intubated and ventilated. However, some practitioners have been lulled into a false sense of ...

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Propofol-based sedation was used in 849 (59.2%) cases; 5 (0.6%) had intestinal perforation. Intestinal perforation was not reported in patients who were sedated with other sedatives. One patient had ...