“You could see little parts of the human cell being broken off,” Ralston said of her very first encounter with the parasite.

A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed. This crucial advance in the fight ...

Influenza viruses are among the most likely triggers of future pandemics. A research team from the Helmholtz Center for Infection Research (HZI) and the Medical Center—University of Freiburg has ...

Current anticancer treatments essentially target the primary tumour cells that proliferate quickly, but do not effectively ...

This approach for transporting therapeutics into cells could open up new possibilities for treating neurological disorders ...

and membrane physiology. Plasma membrane asymmetry and lipid homeostasis The omics era has provided much data on phospholipids, sphingolipids, sterols and proteins located in different membranes, ...

Here, we describe the isolation and structure determination of proteins in membrane vesicles derived directly from cells. Structures of the ion channel Slo1 from total cell membranes and from cell ...

In high-grade DCIS cells, they observed that cell crowding led to an increase in the number of various proteins on the plasma membrane of the cells. In particular, there was a striking 153-fold ...

Mass spectrometry revealed that crowding selectively relocated ion channels, including TRPV4, to the plasma membrane in high-grade DCIS cells. TRPV4 inhibition triggered by crowding decreased ...

Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan Department of Life Sciences, Graduate School of Arts and ...