Metastatic colorectal cancer with microsatellite instability-high or mismatch repair-deficient status represents a distinct ...

Introduction: To design effective small molecule inhibitors targeting the immune checkpoint PD-1/PD-L1 and to explore their inhibitory activity. Methods: In this paper, a total of 69 PD-1/PD-L1 ...

This study aims to investigate whether Rab10-positive domain (Rab10-PD) is expanded during the E phase of infection ... % bromophenol blue (w/v), and 30% glycerol (v/v) followed by Western blot ...

Immune checkpoint inhibitors against PD-1/PD-L1 are highly effective in immunologically hot tumours such as triple-negative breast cancer, wherein constitutive DNA damage promotes inflammation, while ...

This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. This work is licensed under a Creative Commons Attribution 4.0 International ...

It’s taken some time, but games that center around cowboys and indulge in the Western genre are now big hits. Looking to have some fun with 'Red Dead Online'? Here's a look at the 10 best & most ...

Xiaomi has captured the spotlight by releasing the new GTV Smart Projector L1 Pro, an upgrade that pushes home entertainment to new heights. Known for consistently pushing boundaries, Xiaomi’s latest ...

Eagle-eyed viewers of Chicago PD were quick to notice that Detective Kim Burgess was missing from two episodes of the latest season of the police drama – and the character's actress Marina ...

Simply put, the L1, L2, and L3 cache are extremely fast memory layers with L1 being the fastest followed by L2 and L3 cache. However, these unsung heroes have a lot more to their story than just ...

ISRO achieved breakthroughs in reusable technology with two successful landing experiments (RLV-LEX-02 and RLV-LEX-03) in 2024. Conducted in March and June, these tests demonstrated autonomous landing ...