Researchers have developed a novel compound that could be useful for treating bone-destructive diseases. Their study ...

Discover 8 common daily habits that secretly weaken your bones and increase fracture risk. Learn how to protect bone density ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...

Bone-destructive diseases such as osteoporosis and chronic inflammatory arthritis affect millions of people worldwide, causing pain, fractures, and decreased quality of life. These conditions often ...

interact indirectly and directly with important groups of bone cells involved in the bone turnover process (including osteoclasts, osteoblasts and osteocytes) by stimulating the process of bone ...

“Bone strength is based on the balance of two different kinds of cells: Osteoblasts build bones, and osteoclasts break down bones,” Chowdhury explains. Osteoblasts help form the "scaffolding ...

The disease occurs when there's an imbalance between a person's osteoblasts – which are bone-building cells – and their osteoclasts, which are bone-degrading cells. Ordinarily, osteoclasts ...

Excessive activity of 'osteoclasts' or bone-absorbing cells leads to bone loss. Targeting osteoclast differentiation is therefore, a potential therapeutic strategy. In a new study, researchers ...

Bone remodeling is a complex process involving the coordinated actions of osteoblasts and osteoclasts to maintain bone homeostasis. While the influence of osteoblasts on osteoclast differentiation is ...

The cells that help to break down bone tissue are known as osteoclasts, and the cells that help to generate new bone tissue are known as osteoblasts. A protein — RANK ligand, or RANK-L ...

These proteins are cytokines and growth factors. The proteins stimulate the cells that break down bone (osteoclasts) and make them overactive. So, bone is destroyed faster than it's rebuilt. This ...