The latest round of strikes occurred as the United States and its ally Israel struggle to halt a campaign of regional assaults by Yemen’s Houthi militants.

Israel’s military says it intercepted a missile fired toward the country by Yemen’s Houthi rebels. The attack set off sirens late Monday in central areas of Israel, including Tel Aviv.

The Houthis in Yemen launched their fifth missile attack on Israel in a week late Monday, as Israeli officials ratcheted up their warnings to the Iranian-backed group. The Houthis’ repeated attacks show that Israel’s retaliatory strikes and tough talk have failed to deter the group,

Northern Gaza’s last remaining major hospital is now out of service after a raid by Israeli forces severely damaged the building and emptied its wards of patients and doctors.

The Israel Defense Forces continues its intense airstrike and ground campaigns in Gaza. Tensions remain high between Israel and Iran after tit-for-tat long-range strikes in recent months and threats of further military action from both sides.