Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Two major areas of epigenetics—DNA methylation and histone modifications—are known ... the expression of miRNAs has been definitively linked to cancer development, and miRNA profiles can ...

Their rampant use has led to an increase in the prevalence of various chemical toxicity-induced diseases, including hormonal disruption, cancer ... frequency and histone acetylation levels.

the changes in metabolism and the changes in histone methylation and gene expression are the types of changes that can be associated with hormone-receptor negative breast cancer. They're pertinent ...

HDAC3-KO cells exhibited increased histone acetylation and decreased histone methylation. PROTACs showed differential ... Precision targeting of HDAC3 in ovarian cancer [abstract]. In: Proceedings of ...

The field of epigenetics also explains the causal link between certain infectious diseases and cancer, a relationship ... acid N-terminal unstructured histone tails. These modifications, which include ...

Created with MedPeer (medpeer.cn). Future studies investigating chromosomal abnormalities and DCM progression should look at histone acetylation and methylation, as some of the DNA promoter ...

To investigate genetic and epigenetic issues stimulating the evolution of primary trastuzumab resistant and sensitive breast cancer, we compared genomic variation, histone modification and DNA ...

Researchers from the Endocrine Tumors group at the Germans Trias i Pujol Research Institute (IGTP), in collaboration with ...