OBJECTIVE: To document the efficacy of a surgical intensive care unit (SICU)- specific, weight-based dosing protocol of enoxaparin 0.5 mg/kg given subcutaneously every 12 hours for VTE prophylaxis ...

The median calculated twicedaily dose of enoxaparin was 60 mg (range 50–120). The primary outcome (anti-factor Xa level between 0.2 and 0.5 IU/mL) was achieved in 91% of patients (21 of 23 ...