This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

Extra copies of genes involved in DNA damage detection and repair could ... elephants did not have increased PCNA copy number, but agarose gel PCR showed the presence of PCNA pseudogenes. Similar ...

University of Edinburgh scientists have harnessed the power of AI in a new tool that promises to speed up analysis of data ...

With an E-Gel ® iBase™ Power System, separation of DNA can typically be completed in just 7 minutes, perfect for quick analysis of your DNA fragment prior to downstream applications.

In this valuable study, the authors demonstrate that TCF7L2 plays a role in the pathogenesis of cachexia in a mouse model of GI cancer. The results are solid, although future studies will need further ...

The walkaway nature of the agarose gel electrophoresis systems provides substantial labor and cost savings to clinical laboratories. The semi-automated electrophoresis systems are designed for ...

Cell-free DNA (cfDNA), which consists of short DNA fragments released into circulation through apoptosis and necrosis, offers a promising alternative. CfDNA fragmentation patterns are non-random and ...

To identify covalent AKR1C3 inhibitors, we screened compounds in live cells and evaluated the following parameters: (i) covalency via an RJG-2121-mediated competitive activity-based protein profiling ...

This phenomenon may be attributed to the increased energy demands associated with rapid growth and higher feed intake, which could shift the rumen microbial community and fermentation patterns toward ...

Department of Chemistry for Materials, Graduate School of Engineering, Mie University, 1577 Kurimamachiya-Cho, Tsu, Mie 514-8507, Japan ...