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The gas-powered Mercedes-Benz E350 gets 21 mpg overall. We also tested the E320 turbodiesel, which gets 8 miles more per gallon.

Learn More. There are 9 recalls on this vehicle. Learn More. The Mercedes-Benz E350 is a comfortable, quiet and luxurious sedan, with a well-finished interior, comfortable seats and a substantial ...

The E-Class has been the standard bearer for Mercedes-Benz for generations and continues to be at the core of their worldwide sales. The base E350 starts just under $50,000.