A nasal spray that contains esketamine — a potent derivative of ketamine — can now be taken on its own to treat adults with severe depression, the FDA says. Here's what that means.

A ketamine-derived nasal spray is now available for the millions of Americans living with severe depression. The hallucinogenic drug is an option when traditional treatment isn’t working, but it’s not without risk.

The U.S. Food and Drug Administration expanded approval for Johnson & Johnson’s nasal spray, Spravato, to allow it to be used as a standalone treatment for patients with severe depression, the company said on Tuesday.

People with treatment-resistant depression can now take Spravato's ketamine-derived nasal spray as a standalone treatment.

Possessing the drug can lead to a maximum five-year prison sentence and supplying the drug up to 14 years in prison. Ketamine is an effective anaesthetic and plays an important part in battlefield and emergency medicine. It is used to treat pain in end-of-life care and could treat some forms of depression.

Respondents who said they used other drugs recreationally were also likelier to say they used ketamine during the past year than those who reported no past-year drug use.

CIII allows people who have tried at least two oral antidepressants to use the spray on its own – without the need for more medication.

Exploring new treatment avenues has become crucial as mental health challenges such as depression and PTSD continue impacting a significant number of individuals globally. Traditional therapies might not work for everyone,

Johnson & Johnson's ketamine-derived nasal spray has been approved as a standalone treatment to fight depression for those who had an inadequate response to oral antidepressants.

A clinic in Arapahoe County is exploring new ways to help patients by offering ketamine-assisted psychotherapy.

Here's what MDs want you to know about Spravato, the latest FDA-approved standalone nasal spray for depression.

Ketamine therapy has become known for its effects at combating depression and other mood disorders. There’s a growing body of research suggesting it can be especially effective against types