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Lymphangioleiomyomatosis: clinical features, management and basic mechanisms
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Future of academic respiratory medicine: near crisis point
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Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD
Division of Pulmonary Disease and Laboratory of Cytoimmunopathology of Heart and Lung, Salvatore Maugeri Foundation, IRCCS, Veruno, Italy Background: Increased numbers of activated neutrophils have ...
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Quality of Life Questionnaire-Bronchiectasis: final psychometric analyses and determination of minimal important difference scores
Background The Quality of Life-Bronchiectasis (QOL-B), a self-administered, patient-reported outcome measure assessing symptoms, functioning and health-related quality of life for patients with ...
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Online First
Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators ...
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No demonstrable effect of S-carboxymethylcysteine on clearance of secretions from the human lung.
The mucolytic efficacy of S-carboxymethylcysteine has been assessed in a double-blind crossover trial in 16 patients with chronic obstructive bronchitis. No significant difference was found between ...
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Mechanisms of neutrophil transmigration across the vascular endothelium in COPD
Lung Function and Sleep Department, University Hospital Birmingham NHS Foundation Trust, (New) Queen Elizabeth Hospital, Birmingham, UK Correspondence to Dr Jennie Gane, Lung Function and Sleep ...
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Impact of COPD on cardiovascular risk factors and outcomes in people with established cardiovascular disease
Background Little is known about the association between chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) in people with established CVD. Knowing if COPD is associated ...
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Cardiovascular medication use in patients with undiagnosed obstructive sleep apnoea
1 Sleep Disorders Centre, St Boniface General Hospital Research Centre, Section of Respiratory Diseases and Department of Medicine, Winnipeg, Manitoba, Canada 2 Centre for Health Policy and Evaluation ...
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Incidence and characteristics of viral community-acquired pneumonia in adults
Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...
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Inspiratory muscle training to enhance recovery from mechanical ventilation: a randomised trial
Background In patients who have been mechanically ventilated, inspiratory muscles remain weak and fatigable following ventilatory weaning, which may contribute to dyspnoea and limited functional ...
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Development of the bronchial epithelial reticular basement membrane: relationship to epithelial height and age
Background The bronchial epithelium and underlying reticular basement membrane (RBM) have a close spatial and functional inter-relationship and are considered an epithelial–mesenchymal trophic unit ...