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The tumor microenvironment (TME) consists of a complex mix of cellular and non-cellular components, including immune cells, ...
The tumor microenvironment (TME ... They contribute to crucial processes such as immune evasion, angiogenesis, metabolic reprogramming, and the maintenance of cancer stem cells, and their ...
Given the importance of CNP in angiogenesis, researchers reasoned ... is a successful approach to target the immunosuppressive tumor microenvironment, which should lead to a breakthrough in ...
Tumor cells undergoing epithelial–mesenchymal transition (EMT) can profoundly modulate their microenvironment ... tumor progression by decreasing angiogenesis, tumor growth and the EMT-promoting ...
The Xerna TME panel looks at the biologies of the tumor microenvironment that are relevant to large numbers of patients, with a focus on angiogenesis and immune processes. Using a machine-learning ...
Prostate-specific membrane antigen (PSMA) gene expression predicts angiogenesis and response to tyrosine kinase inhibitors (TKIs) in patients with metastatic clear cell renal cell carcinoma (RCC), ...
fueled a myeloid-rich tumor microenvironment in mice, and resulted in the promotion of tumor organoid growth. TI-CH increased the risk of disease recurrence or death among patients with NSCLC and ...
Tempest Therapeutics, Inc. (Nasdaq: TPST), a clinical-stage biotechnology company developing first-in-classi targeted and ...
The National Foundation for Cancer Research (NFCR) congratulates Dr. Rakesh K. Jain on receiving the 2025 AACR Award for Lifetime Achievement in Cancer Research. A globally recognized leader in ...
“Together, these findings highlight how our vaccines act at multiple levels within the tumor microenvironment to drive more effective anti-tumor responses.” IO102-IO103, a dual-antigen vaccine ...
Preclinical data further support the potential of dual-antigen and TGF-β-directed vaccines to reshape the tumor microenvironment and drive anti-tumor immunity NEW YORK, April 25, 2025 (GLOBE ...