system and devised a fine-tuning method for chromatin loop prediction (Figure 1). The result showed DNABERT could be used to predict the ChIA-PET experiments with high precision, and the DHL ...

How does cohesin get past the CBE obstacles on the chromatin that naturally prevent loop formation over long distances? "We found that shutting down the CBEs allows cohesin to move large regions ...

In a study published in Cell Reports, they and their colleagues show that the chromatin environment on ... feedback transcription factor activation loop that prevents differentiation.

New study provides the first comprehensive and complimentary overview on the physical and functional interactions of the human transcription factors. Transcription factors (TFs) are the most essential ...