For Lions defensive coordinator Aaron Glenn's money, 49ers star George Kittle is the best tight end in football.

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

As Brock Purdy celebrated his 25th birthday Friday, the 49ers struggled to field and coach up healthy offensive lineman ahead ...

Moody is 15-for-15 in field goal attempts at home, starting off 6-for-6 in the opener against the New York Jets. But Moody ...

The Lions held a 17-point lead in the NFC championship game over the San Francisco 49ers before getting outscored 27-7 in the ...

When the San Francisco 49ers used a third-round pick to draft Jake Moody last year, the hope was it would settle their ...

On the day the San Francisco 49ers were eliminated from playoff contention, they delivered a performance that summed up their ...

Coach Dan Campbell stood at the podium after Detroit blew a 17-point lead to San Francisco in last season’s NFC title game ...

Tua Tagovailoa threw for 215 yards and a touchdown, Jason Sanders nailed five field goals, and the Miami Dolphins kept their ...

Detroit Lions defensive coordinator Aaron Glenn called San Francisco 49ers TE George Kittle 'the best tight end in the game.' ...

As Shanahan projected Monday, Guerendo is returning to the practice field ... The 49ers placed Williams (ankle) on injured reserve Thursday. Williams had missed San Francisco's past four games ...