The tumor microenvironment (TME ... are involved in processes critical to tumor progression, such as remodeling of the ECM, immune cell infiltration, angiogenesis, and stromal-tumor communication.

From a meeting that celebrates basic research and being "first," a look at 3 data sets on therapies that would break new ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

Mapping a tumor's cellular neighborhood in three dimensions could identify potential targets for personalized cancer therapy.

partial degradation and remodeling of the ECM. Tumors hijack normal tissue development programs such as repair and regeneration, but use these programs in a deregulated manner to mediate ...

We identify an age-related subpopulation of RETNLγ + LCN2 + senescence-like neutrophils (RLSNs) that preferentially accumulate in the tumor microenvironment ... Mmp14b in ECM remodeling to ...