More information: Abstract no: 12, "On-target mutations drive resistance to WRN helicase inhibitors in microsatellite ...
Although pembrolizumab is approved for deficient mismatch repair or microsatellite instability-high (dMMR/MSI-H) tumors regardless of histology, there is a paucity of data to support its effectiveness ...
Microsatellite instability (MSI) is a “striking” prognostic factor for patients with gastric cancer, even after controlling for clinicopathologic characteristics, according to researchers. The ...
What Is a Brain Tumor? A brain tumor (also called an intracranial tumor) is a cluster of abnormal cells that grows in or around your brain. There are over a hundred types of tumors that develop in ...
The FDA recently approved a phase 2 clinical trial to investigate the efficacy of leronlimab in patients with relapsed or ...
Nimbus Therapeutics LLC reported the identification of an allosteric, potent, selective, highly efficacious and noncovalent Werner syndrome helicase (WRN) inhibitor, NTX-452, for the potential ...
Nov. 4, 2024 — Researchers have uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. These targets were identified through a screen ...
DCC protein loss can also be examined by immunohistochemistry. DNA ploidy is a test that measures the DNA content within tumor cells. Normal cells in the resting state contain a complete set of ...
Oct. 30, 2024 — A new analysis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -- and the cells of a tumor ...
Thyroid cancer is a type of cancer that starts in your thyroid gland. A gland is an organ in your body that makes a substance. Your thyroid is shaped like a small butterfly and is found inside the ...
(ends) Abstract no: 12, “On-target mutations drive resistance to WRN helicase inhibitors in microsatellite unstable colorectal cancer”, by Gabriele Picco, presented in plenary session 7 ...