directly prevents oligodendrocyte death in animal models of MS. We also demonstrate that this therapeutic effect complements endogenous LIF receptor signaling, which already serves to limit ...

SEATTLE--(BUSINESS WIRE)--Receptor Life Sciences (RLS), a pharmaceutical company developing innovative therapies to address central nervous system disorders, announced the U.S. Food and Drug ...

N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by glutamate, an excitatory neurotransmitter. These receptors are located mostly at excitatory synapses and ...

Trophoblast cells of all pregnancy stages express receptors for IL-6-like cytokines ... Members of the IL-6 cytokine family including leukemia inhibitory factor (LIF), IL-6 and IL-11 have been ...