Moreover, Integrin signaling is associated with ... regulation and variations in tumor-stromal interactions in the tumor microenvironment — can result in the development and/or advancement ...

Here we show that codeletion of the p53 and αv integrin genes in mouse stratified ... but also prevents remodeling of the tumor microenvironment and delays tumor growth. We observed that Akt ...

In our previous study, using the representational difference analysis technique, ITGA11 (integrin α11, α11) was among the top six genes identified as differentially expressed in non-small cell ...

To effectively battle cancer, scientists must study the battlefield. Now, in a recent study published in Nature ...

Their role in shaping the complex interactions between cancer cells and their microenvironment makes them vital for sustaining tumor development. Additionally, lncRNAs regulate processes such as ...

Tumor microenvironment (TME) plays a pivotal role in malignant progression and metastatization in several tumors, including ...

Tumor cells undergoing epithelial–mesenchymal transition (EMT) can profoundly modulate their microenvironment via enhanced secretion of multiple soluble factors, including IL-8, IL-6 ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, extracellular matrix (ECM), cytokines, and growth factors, all interacting ...

A new study has identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia. The paper is published in Nature.

fueled a myeloid-rich tumor microenvironment in mice, and resulted in the promotion of tumor organoid growth. TI-CH increased the risk of disease recurrence or death among patients with NSCLC and ...