Epigenetics and Cancer The first human disease to ... The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate ...

Senior author Manel Esteller of the Spanish National Cancer Center in Madrid and colleagues ... The researchers analyzed the twins' global DNA methylation and histone H3 and H4 acetylation in samples ...

There is a growing awareness that epigenetic dysregulation plays a significant role in many types of cancer ... Modifications include acetylation, phosphorylation and methylation.

Cancer is a major focus of the review ... atherosclerosis is particularly highlighted, with changes in histone acetylation and methylation found in atherosclerotic tissues. Environmental exposure ...