Ubiquitin-like proteins (UBLs) such as NEDD8 are transferred to their targets by distinct, parallel, multienzyme cascades that involve the sequential action of E1, E2 and E3 enzymes. How do ...

E2 ubiquitin-conjugating enzyme receives the activated ubiquitin from E1 and transfers it to a substrate bound to a third enzyme, an E3 ubiquitin-protein ligase. A degradation signal, or 'degron ...

GM Authority discovered nine new trademark filings with the United States Patent and Trademark Office (USPTO) for Electra E1 through E9 names. Filed on October 27, General Motors' applications are ...