Donte DiVincenzo will not play Friday night when the Timberwolves visit Madison Square Garden for a matchup with Karl-Anthony Towns and the Knicks. His absence could pose significant challenges for Minnesota.

Karl-Anthony Towns likely is the player the Knicks can least do without, especially with Mitchell Robinson still unable to practice.

Knicks center Karl-Anthony Towns is questionable to face his former team Friday with a sprained right thumb, while Minnesota’s Donte DiVincenzo will miss his return to Madison Square Garden with a toe injury.