Semiconservative replication was not the only model ... DNA unwinding at a single spot on the chromosome known as the replication origin. As the double helix unwinds, it creates a loop known ...

Deoxyribonucleic acid (DNA) replication is fundamental ... disrupting base pairing through loop-mediated interactions. The alignment of structural models with functional assays confirmed that ...

Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in ...

As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication. As shown in Figure 1, when the double helix ...