It is estimated that more than 5 million people worldwide suffer from ulcerative colitis, a chronic inflammation of the colon ...

Proteins play a vital role in human health and detecting them is crucial in medical research and clinical practice.

These vesicles form by budding into the lumen of the MVB. The content of MVBs can be degraded, via fusion with lysosomes, or released into the extracellular space, via fusion with the plasma membrane.

More information: Xiuming Liang et al, Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors, Nature Communications (2025 ...

Imaging-based nanophotonic sensors using dielectric and plasmonic metasurfaces enable sensitive, label-free detection of ...

Extracellular vesicles (EVs) shuttle important biologically active molecules out of cells. Characterizing their size, density, biochemical composition, and cell of origin provide researchers with ...

Eukaryotic and prokaryotic cells produce minute (40-1000 nm) membrane vesicles that are released into the local environment. These extracellular vesicles (EVs), including exosomes and microvesicles, ...

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the ...

By using tiny, naturally occurring particles called extracellular vesicles (EVs), they have created a way to boost the body's immune system to fight tumors more effectively. This breakthrough ...

Discover a study that has revealed a new potential mechanism of understanding inflammation in ulcerative colitis.

Engineered extracellular vesicles incorporating a viral fusogenic protein and bacterial intein enable efficient intracellular delivery of therapeutic proteins and RNA.