The volume of lentiviral vector added depends on the titer ... transfer an appropriate volume into a new six-well plate with feeders. hiPS cells can be passaged with a 1:2–1:6 split ratio ...

They are non-integrating vectors so expression in dividing cells is progressively lost. First generation vectors may be suitable for applications where transient, high level activity is sufficient, ...

Kite first telegraphed its plans to tackle viral vector production solo in 2019. The company at the time declined to name its investment in the site or how many employees it aimed to recruit. In ...

AstraZeneca has entered the “off-the-shelf” cell therapy space, penning a $1 billion deal to acquire EsoBiotec and its lentiviral vector platform. The deal will see AstraZeneca scoop up all ...

The well-established platform allows for the ability to support the exacting viral vector manufacturing needs of the NCH NK cells created on the hospital's patented universal-donor NK cell platform.

The facility, which was previously used by Novartis to manufacture the gene therapy Zolgensma, was picked up by BMS in early 2023 to bolster viral vector capacity for its commercial cell therapy ...

enabling full-plate usage and increased well-to-well cell consistency for improved productivity in cell culture assays at a cost comparable to a standard 96-well plate. The Thermo Scientific Nunc Edge ...

delivers new solutions to those developing essential viral vector purification and analytical tools. “The promise of cell and gene therapies is being constrained by the high cost in producing ...