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Researchers have created a groundbreaking 3D-printed artificial tumor tissue capable of replicating the in vivo conditions of ...
To effectively battle cancer, scientists must study the battlefield. Now, in a recent study published in Nature ...
CTLA-4 inhibitor ADG126 can be dosed at 20 mg/kg Q6W in combination with pembrolizumab with In combination with pembrolizumab, ADG126 showed a 29% confirmed overall response rate (ORR) in microsatelli ...
One patient with microsatellite instability-high metastatic CRC refractory to anti-PD ... is sufficient to overcome the immunosuppressive tumor microenvironment or whether combination strategies ...
CytomX Therapeutics reveals promising CX-2501 results & strengthens finances with $100M offering. Key updates on cancer ...
Ultimately, incorporating such validated, CRC-specific criteria into updated testing guidelines will be crucial for advancing precision oncology care in colorectal cancer. Elethia W. Tillman has a ...
“Anti-tumor immune cells are also challenged by nutrient limitation in tumors.” Nutrient limitation in the tumor microenvironment can lead to the metabolic suppression of effector immune cells, ...
The numbers don’t lie: Colorectal cancer (CRC) has been on the rise in younger people in the United States for over two decades. The new analysis found that childhood exposure to a carcinogenic ...
A joint research team affiliated with UNIST has developed a 3D-printed artificial tumor tissue capable of replicating the in ...
Abstract Heterogeneity and the absence of a tumor microenvironment (TME) in traditional patient-derived organoid (PDO) cultures limit their ...