The aldolase reaction is a classic case for a ... are found in most genomes of archaea and early bacterial lineages. A structure of the enzyme from S. tokodaii revealed a novel tertiary structure ...

Evolutionary advances are often fueled by unanticipated innovation. Directed evolution of a computationally designed enzyme suggests that pronounced molecular changes can also drive the ...

Energy in a trap This is where aldolase A comes in. If it is switched off, fructose bisphosphate accumulates in the cell, and ...