Kotlik is a city in Kusilvak Census Area, Alaska, United States. At the 2010 census the population was 577, down from 591 in 2000. Kotlik is located at 63°02′09″N 163°33′37″W / 63.035769°N 163.560177°W. Kotlik is located on the east bank of the Kotlik Slough, 35 miles northeast of Emmonak in the Yukon-Kuskokwim Delta.