Interstitial lung disease in dermatomyositis and polymyositis ...
WEBFeb 2, 2024 · APPROACH TO THERAPY. When determining the need for treatment in patients with ILD due to PM or DM, we assess the severity of respiratory impairment and the rate of progression.
Interstitial lung disease in dermatomyositis and ... - UpToDate
WEBAug 22, 2024 · Dermatomyositis (DM) and polymyositis (PM) are classified as idiopathic inflammatory myopathies. Among patients with DM or PM, interstitial lung disease (ILD) is a major cause of morbidity and mortality. A general approach to the evaluation of ILD is provided separately.
Diagnosis and Management of Myositis-Associated Lung Disease
WEBFeb 8, 2023 · Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis
Myositis-associated interstitial lung disease: a comprehensive …
WEBEvidence for the use of cyclophosphamide in the treatment of myositis-ILD is limited to retrospective case series, and our practice is to favour alternative steroid-sparing agents given concerns for its underlying toxicity.
WEBdiagnosis of DM is made, and treatment recommendations for patients with DM based on disease severity, the presence of systemic symptoms, and myositis-specific antibody (MSA) profiles. This review emphasizes
Management of Myositis-Associated Interstitial Lung Disease
WEBApr 3, 2021 · Patients with anti-ARS antibody-positive ILD respond better to GC treatment, but with frequent recurrence; thus, GCs plus immunosuppressants (TAC, CsA, azathioprine, and mycophenolate mofetil) are often needed in …
Dermatomyositis: Diagnosis and treatment - Journal of the …
WEBThe treatment approach proposed by this continuing medical education series discusses both established and novel therapies for DM and highlights the importance of considering lesion type, degree of muscle involvement, presence of systemic symptoms, presence of MSAs, and patient age when determining the best treatment approach for a …
WEBThe classification and treatment of patients with myositis-associated ILD remains challenging. A standardized therapeutic approach to these patients is lacking, and prospective studies in the field are needed to determine optimal treatment regimens.
Management of Myositis-Associated Interstitial Lung Disease
WEBApr 3, 2021 · Patients with anti-ARS antibody-positive ILD respond better to GC treatment, but with frequent recurrence; thus, GCs plus immunosuppressants (TAC, CsA, azathioprine, and mycophenolate mofetil) are often needed in …
Myositis-Related Interstitial Lung Disease: A Respiratory …
WEBJun 10, 2021 · Rapidly progressing anti-melanoma differentiation-associated gene 5 antibody-positive ILD may require rapid multi-drug therapy, while anti-aminoacyl tRNA synthetase (ARS) antibody-positive ILD can be treated with anti-inflammatory drugs. Importantly, however, anti-ARS antibody-positive ILD …